MYO5A Polyclonal Antibody

Background:
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Research Area: Metabolism, Neuroscience, Signal Transduction

Synonyms:
MYO5A, GS1, MYH12, MYO5, MYR12, myosin VA

Immunogen: Recombinant fusion protein of human MYO5A (NP_000250.3).

Swissprot: Q9Y4I1
Gene ID: 4644

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/32325088/