MYO5B Blocking Peptide (N-Term)
€363.00
In stock
SKU
AC-BP21849a
Background:
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
Other Names:
Unconventional myosin-Vb, MYO5B, KIAA1119
Target/Specificity:
The synthetic peptide sequence is selected from aa 17-30 of HUMAN MYO5B
Gene Name: MYO5B
Gene ID: 4645
Primary Accession: Q9ULV0
Other Accession: P21271;P70569
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
Other Names:
Unconventional myosin-Vb, MYO5B, KIAA1119
Target/Specificity:
The synthetic peptide sequence is selected from aa 17-30 of HUMAN MYO5B
Gene Name: MYO5B
Gene ID: 4645
Primary Accession: Q9ULV0
Other Accession: P21271;P70569
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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