MYO5C Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP6354a
Background:
The MYO5C gene encodes a 1,742-amino acid protein with a predicted molecular mass of 203 kD that shares approximately 50% identity with family members MYO5A (160777) and MYO5B (606540). The MYO5C protein consists of a motor domain followed by 6 IQ motifs, a coiled-coil region, and a C-terminal globular domain. MYO5C contains a serine residue conserved among all 3 class V myosins whose phosphorylation in MYO5A regulates melanosome binding; however, MYO5C does not contain the PEST region present in MYO5A and MYO5B.Myo5c was found specifically in the apical regions of intestinal epithelial cells and in exocrine pancreas.
Other Names:
Unconventional myosin-Vc, MYO5C
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6354a was selected from the Center region of human MYO5C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MYO5C
Gene ID: 55930
Primary Accession: Q9NQX4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The MYO5C gene encodes a 1,742-amino acid protein with a predicted molecular mass of 203 kD that shares approximately 50% identity with family members MYO5A (160777) and MYO5B (606540). The MYO5C protein consists of a motor domain followed by 6 IQ motifs, a coiled-coil region, and a C-terminal globular domain. MYO5C contains a serine residue conserved among all 3 class V myosins whose phosphorylation in MYO5A regulates melanosome binding; however, MYO5C does not contain the PEST region present in MYO5A and MYO5B.Myo5c was found specifically in the apical regions of intestinal epithelial cells and in exocrine pancreas.
Other Names:
Unconventional myosin-Vc, MYO5C
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6354a was selected from the Center region of human MYO5C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MYO5C
Gene ID: 55930
Primary Accession: Q9NQX4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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