MYO6 Polyclonal Antibody

Background:
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Area: Cancer, Signal Transduction

Synonyms:
MYO6, DFNA22, DFNB37, Myo6-007, Myo6-008, myosin VI

Immunogen: Recombinant fusion protein of human MYO6 (NP_004990.3).

Swissprot: Q9UM54
Gene ID: 4646

Calculated MW: 145 kDa/146 kDa/148 kDa/149 kDa
Observed MW: 150 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.