MYOC antibody (clone 2B4), anti-human

Background:
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Other Names:
Myocilin, Myocilin 55 kDa subunit, Trabecular meshwork-induced glucocorticoid response protein, Myocilin, N-terminal fragment, Myocilin 20 kDa N-terminal fragment, Myocilin, C-terminal fragment, Myocilin 35 kDa N-terminal fragment, MYOC, GLC1A, TIGR

Antigen Type:
Recombinant Protein

Gene Name: MYOC
Gene ID: 4653
NCBI Accession: NP_000252.1
Primary Accession: Q99972
Other Accession: BC029261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .