MYOC polyclonal, anti-human, mouse, rat

Background:
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Synonyms: GLC1A, GPOA, JOAG, JOAG1, TIGR

Cellular Location: Golgi apparatus Golgi apparatus Mitochondrion secreted

Immunogen:
Recombinant protein of human MYOC

Gene Symbol: MYOC

Gene ID: 4653

Swiss prot: Q99972

Calculated MW: 57kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.