MYOC Polyclonal Antibody

Background:
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Research Area: Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
MYOC, GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin

Immunogen: Recombinant fusion protein of human MYOC (NP_000252.1).

Swissprot: Q99972
Gene ID: 4653

Calculated MW: 56 kDa
Observed MW: 65 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.