MYO6 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP51374
Catalog Number: AC-AP54320
Size: 100 µl
Host: Rabbit
Applications: IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Size: 100 µl
Host: Rabbit
Applications: IHC-P, IHC-F, IF, ICC, E
Datasheet
Request Information
Background:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells (By similarity).
Other Names:
Unconventional myosin-VI, Unconventional myosin-6, MYO6, KIAA0389
Antigen Type: synthetic peptide
Antigen Type: MYO6 (HGNC:7605)
Gene ID: 4646
Primary Accession: Q9UM54
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells (By similarity).
Other Names:
Unconventional myosin-VI, Unconventional myosin-6, MYO6, KIAA0389
Antigen Type: synthetic peptide
Antigen Type: MYO6 (HGNC:7605)
Gene ID: 4646
Primary Accession: Q9UM54
| Is Featured? | No |
|---|
Write Your Own Review