Myosin IXb Polyclonal Antibody

Background:
myosin IXB(MYO9B) Homo sapiens This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

Alternative Names:
MYO9B, MYR5, Unconventional myosin-IXb, Unconventional myosin-9b

Immunogen: The antiserum was produced against synthesized peptide derived from human MYO9B. AA range:304-353

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 250

GeneID: MYO9B

Storage: -20°C/1 year

NOTE: For Research Use Only