Myosin (slow) (clone IML-64), anti-human, mouse, rat

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Cell Communication

Description:
Myosin is a hexameric protein involved in muscle contraction, which consists of two heavy chains (200kDa), and four light chains (20kDa): two phosphorylated regulatory subunits (MLC2) and two non-phosphorylated subunits (alkali or MLC1 and MLC3 types). Myosin (slow) (myosin light chain 1, slow-twitch muscle B/ventricular isoform, also called MYL3) is mapped to the region 3p. Defects in MYL3 are the cause of familial hypertrophic cardiomyopathy type 8 (CMH8).

Alternate Names: Myosin light chain 3, Cardiac myosin light chain 1, CMLC1, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Ventricular/slow twitch myosin alkali light chain, MYL3

Application Notes: E: 1:1,000-1:2,000; WB: 1:500-1:2,000; IHC: 1:200-1:1,000

Accession No.: P08590

Antigen: Human skeletal muscle myosin purified from myofibrils.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.