Myosin VIIa polyclonal, anti-human
€305.00
In stock
SKU
BS60184
Background:
Myosins are molecular motors that move along filamentous Actin and influence cellular movements such as phagocytosis. There are seven classes of myosins in vertebrates, including Myosin II, and six unconventional Myosin classes, designated I, V, VI, VII, IX and X. Myosin VIIa is a plus end-directed motor that influences cilia formation and cell adhesion. Mutations in the human Myosin VIIa gene correlate with Usher syndrome, a disease characterized by congenital sensorineural deafness, vestibular dysfunction and retinitis pigmentosa.
Alternative Name:
Unconventional myosin-VIIa, MYO7A, USH1B
Application Dilution: WB: 1:500~1:1000
Specificity: Myosin VIIa polyclonal antibody detects endogenous levels of Myosin VIIa protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Myosin VIIa.
MW: ~ 254 kDa
Swis Prot.: Q13402
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Myosins are molecular motors that move along filamentous Actin and influence cellular movements such as phagocytosis. There are seven classes of myosins in vertebrates, including Myosin II, and six unconventional Myosin classes, designated I, V, VI, VII, IX and X. Myosin VIIa is a plus end-directed motor that influences cilia formation and cell adhesion. Mutations in the human Myosin VIIa gene correlate with Usher syndrome, a disease characterized by congenital sensorineural deafness, vestibular dysfunction and retinitis pigmentosa.
Alternative Name:
Unconventional myosin-VIIa, MYO7A, USH1B
Application Dilution: WB: 1:500~1:1000
Specificity: Myosin VIIa polyclonal antibody detects endogenous levels of Myosin VIIa protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Myosin VIIa.
MW: ~ 254 kDa
Swis Prot.: Q13402
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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