MYOT polyclonal, anti-human, mouse, rat

Background:
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Synonyms: LGMD1, LGMD1A, MFM3, TTID, TTOD

Cellular Location: Cytoskeleton Plasma membrane

Immunogen:
Recombinant protein of human MYOT

Gene Symbol: MYOT

Gene ID: 9499

Swiss prot: Q9UBF9

Calculated MW: 55kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.