MYOT Polyclonal Antibody

Background:
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Research Area: Cancer, Cardiovascular, Signal transduction

Synonyms:
MYOT, LGMD1, LGMD1A, MFM3, TTID, TTOD, myotilin

Immunogen: Recombinant fusion protein of human MYOT (NP_001129412.1).

Swissprot: Q9UBF9
Gene ID: 9499

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.