MYOZAP polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254439
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
MYOZAP, also known as GRINL1A, is a 54kDa highly conserved cardiac protein . It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase–RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Alternate Names: Myocardium-enriched zonula occludens-1–interacting protein, glutamate receptor ionotropic N-methyl D-aspartate-like 1A, GRINL1A, GCOM1, Gup, Gup1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_001018110
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human MYOZAP.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
MYOZAP, also known as GRINL1A, is a 54kDa highly conserved cardiac protein . It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase–RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
Alternate Names: Myocardium-enriched zonula occludens-1–interacting protein, glutamate receptor ionotropic N-methyl D-aspartate-like 1A, GRINL1A, GCOM1, Gup, Gup1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_001018110
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human MYOZAP.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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