MYPT3 Polyclonal Antibody

Background:
protein phosphatase 1 regulatory subunit 16A(PPP1R16A) Homo sapiens Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c. [provided by RefSeq, Jul 2016],

Alternative Names:
PPP1R16A, MYPT3, Protein phosphatase 1 regulatory subunit 16A, Myosin phosphatase-targeting subunit 3

Immunogen: The antiserum was produced against synthesized peptide derived from human PPP1R16A. AA range:362-411

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 60

GeneID: PPP1R16A

Storage: -20°C/1 year

NOTE: For Research Use Only