MYSM1 polyclonal (N-term), anti-human, mouse

MYSM1 polyclonal (N-term), anti-human, mouse

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In stock
SKU
AC-AP10517a
Catalog Number: AC-AP10517a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB27661
Applications: FC, WB
Datasheet

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Background:
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Other Names:
Histone H2A deubiquitinase MYSM1, 2A-DUB, 3419-, Myb-like, SWIRM and MPN domain-containing protein 1, MYSM1, KIAA1915

Target/Specificity:
This MYSM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human MYSM1.

Antigen Region:
111-139

Antigen Type: Synthetic Peptide

Gene Name: MYSM1
Gene ID: 114803
Primary Accession: Q5VVJ2
NCBI Accession: NP_001078956.1
Other Accession: Q69Z66; NP_001078956.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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