n-Myc polyclonal, anti-human, rat

Quantity: 100 µg

Background:
N-myc proto-oncogene protein, also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene. This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. And this protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for N-myc proto-oncogene protein (MYCN) detection. Tested with WB in Human, Rat.

Synonyms:
bHLHe37 antibody, Class E basic helix-loop-helix protein 37 antibody, MODED antibody, mycn antibody, MYCN_HUMAN antibody, N myc antibody, N myc proto oncogene protein antibody, N-myc proto-oncogene protein antibody, Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene antibody, Neuroblastoma MYC oncogene antibody, NMYC antibody, NMYC proto oncogene protein antibody, ODED antibody, Oncogene NMYC antibody, pp65/67 antibody, v myc avian myelocytomatosis viral related oncogene neuroblastoma derived antibody, v myc myelocytomatosis viral related oncogene neuroblastoma derived antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human n-Myc (428-464aa EYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC), different from the related mouse and rat sequences by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human n-Myc (428-464aa EYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC), different from the related mouse and rat sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.