N4BP2 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region| and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed| developmentally downregulated 4| (Nedd4) proteins. This protein binds and hydrolyzes ATP| may function as a 5'-polynucleotide kinase| and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Tags & cell markers

Synonyms: N4BP2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year