Na+ CP type II Alpha polyclonal antibody, anti-human, mouse, rat

Background:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN2A encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in SCN2A have been linked to several seizure disorders. Several alternatively spliced transcript variants of SCN2A have been described, but the full-length nature of some of these variants has not been determined.

Research Area: Neuroscience

Synonyms: SCN2A, NAC2, SCN2A1, SCN2A2, Sodium channel protein type 2 subunit alpha, HBSC II, Sodium channel protein brain II subunit alpha, Sodium channel protein type II subunit alpha, Voltage-gated sodium cha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year