Na+ CP type IV Alpha polyclonal antibody, anti-human, mouse, rat

Background:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. SCN4A (sodium voltage-gated channel alpha subunit 4) encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in SCN4A have been linked to several myotonia and periodic paralysis disorders.

Research Area: Neuroscience

Synonyms: SCN4A, Sodium channel protein type 4 subunit alpha, SkM1, Sodium channel protein skeletal muscle subunit alpha, Sodium channel protein type IV subunit alpha, Voltage-gated sodium channel subunit alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year