Na+/K+-ATPase alpha1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers

Synonyms:
A1A1, AT1A1, AT1A1, ATP1A1, Atpa-1, ATPase Na+/K+ transporting alpha 1 polypeptide, ATPase Na+/K+ transporting subunit alpha 1, BC010319, EC 3.6.3.9, MGC3285, MGC38419, MGC51750, Na K ATPase alpha A catalytic polypeptide, Na K ATPase catalytic subunit alpha A protein, Na(+)/K(+) ATPase 1, Na(+)/K(+) ATPase alpha-1 subunit, Na+, K+ ATPase alpha subunit, Na+/K+ ATPase alpha 1 subunit, Na+/K+ ATPase 1, Na, K ATPase alpha 1 subunit, Nkaa1b, Sodium potassium ATPase alpha 1 polypeptide, Sodium pump 1, Sodium pump subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1

Immunogen: KLH conjugated Synthetic peptide corresponding to human ATP1A1

Swissprot: P05023,Q8VDN2,P06685

Calculated MW: 113 kDa
Observed MW: 100 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:300-1:800

Storage:
Store at -20°C. Avoid freeze / thaw cycles.