NAE1 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13067c
Background:
The protein encoded by this gene binds to the beta-amyloidprecursor protein. Beta-amyloid precursor protein is a cell surfaceprotein with signal-transducing properties, and it is thought toplay a role in the pathogenesis of Alzheimer's disease. Inaddition, the encoded protein can form a heterodimer with UBE1C andbind and activate NEDD8, a ubiquitin-like protein. This protein isrequired for cell cycle progression through the S/M checkpoint.Three transcript variants encoding different isoforms have beenfound for this gene.
Other Names:
NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Gene Name: NAE1
Gene ID: 8883
Primary Accession: Q13564
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene binds to the beta-amyloidprecursor protein. Beta-amyloid precursor protein is a cell surfaceprotein with signal-transducing properties, and it is thought toplay a role in the pathogenesis of Alzheimer's disease. Inaddition, the encoded protein can form a heterodimer with UBE1C andbind and activate NEDD8, a ubiquitin-like protein. This protein isrequired for cell cycle progression through the S/M checkpoint.Three transcript variants encoding different isoforms have beenfound for this gene.
Other Names:
NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Gene Name: NAE1
Gene ID: 8883
Primary Accession: Q13564
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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