NAE1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms: A-116A10.1, APPBP1, HPP1, ula-1

Cellular Location: Plasma membrane

Immunogen:
Recombinant protein of human NAE1

Gene Symbol: NAE1

Gene ID: 8883

Swiss prot: Q13564

Calculated MW: 60kDa

Recommended dilution:
WB 1:1000-4000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.