NAE1 Polyclonal Antibody

Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
59 kDa, A 116A10.1, Amyloid beta precursor protein binding protein 1 59kD, Amyloid beta precursor protein binding protein 1 59kDa, Amyloid beta precursor protein binding protein 1, Amyloid beta precursor protein binding protein 1, 59 kDa, Amyloid beta precursor protein-binding protein 1, Amyloid protein binding protein 1, Amyloid protein-binding protein 1, APP BP1, APP-BP1, APPBP 1, APPBP1, HPP 1, HPP1, NAE 1, NAE1, NEDD8 activating enzyme E1 regulatory subunit, NEDD8 activating enzyme E1 subunit 1, NEDD8 activating enzyme E1 subunit, NEDD8-activating enzyme E1 regulatory subunit, Proto oncogene protein 1, Proto-oncogene protein 1, Protooncogene protein 1, ula 1, ULA1

Immunogen: Recombinant protein of human NAE1

Swissprot: Q13564
Gene Accession: BC000480

Calculated MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-79844/sc-79843/sc-130690