NAE1 Polyclonal Antibody

Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
NAE1, A-116A10.1, APPBP1, HPP1, ula-1

Immunogen: Recombinant fusion protein of human NAE1 (NP_003896.1).

Swissprot: Q13564
Gene ID: 8883

Calculated MW: 50 kDa/59 kDa/60 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:4000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.