NAE1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP13067c
Catalog Number: AC-AP13067c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33003
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33003
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Other Names:
NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Target/Specificity:
This NAE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human NAE1.
Antigen Region:
172-200
Antigen Type: Synthetic Peptide
Gene Name: NAE1
Gene ID: 8883
Primary Accession: Q13564
NCBI Accession: NP_001018169.1;NP_001018170.1;NP_003896.1
Other Accession: Q9Z1A5; Q4R3L6; NP_001018170.1; NP_003896.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Other Names:
NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
Target/Specificity:
This NAE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human NAE1.
Antigen Region:
172-200
Antigen Type: Synthetic Peptide
Gene Name: NAE1
Gene ID: 8883
Primary Accession: Q13564
NCBI Accession: NP_001018169.1;NP_001018170.1;NP_003896.1
Other Accession: Q9Z1A5; Q4R3L6; NP_001018170.1; NP_003896.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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