NAL11 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP9991a
Background:
NAL11 are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NAL11 are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes.
Other Names:
NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6, NLRP11, NALP11, NOD17, PAN10, PYPAF6
Gene Name: NLRP11
Gene ID: 204801
Primary Accession: P59045
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NAL11 are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NAL11 are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes.
Other Names:
NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6, NLRP11, NALP11, NOD17, PAN10, PYPAF6
Gene Name: NLRP11
Gene ID: 204801
Primary Accession: P59045
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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