NAL12 Rabbit polyclonal antibody, anti-human, mouse

Background:
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein| which contains an N-terminal pyrin domain| a NACHT domain| a NACHT-associated domain| and a C-terminus leucine-rich repeat region| functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Research Area: Cell biology, Signal transduction

Synonyms: NAL12

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year