NALP8 polyclonal, anti-human

NALP8 polyclonal, anti-human

€484.00
In stock
SKU
254348
Catalog Nr.: 254348
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB
Datasheet
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Protein Family: Enzymes

Pathway and Disease: Signaling Molecules and Interaction

Description:
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.

Alternate Names: NALP8, NACHT, LRR and PYD domains-containing protein 8, NLRP8, NOD16, CLR19.2, PAN4

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: NP_789781

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human NALP8.

Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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