NAMPT polyclonal (Center), anti-human

NAMPT polyclonal (Center), anti-human

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In stock
SKU
AC-AP9010c
Catalog Number: AC-AP9010c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22920
Applications: WB, IHC-P
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Background:
NAMPT catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Other Names:
Nicotinamide phosphoribosyltransferase, NAmPRTase, Nampt, Pre-B-cell colony-enhancing factor 1, Pre-B cell-enhancing factor, Visfatin, NAMPT, PBEF, PBEF1

Target/Specificity:
This NAMPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the Central region of human NAMPT.

Antigen Region:
400-426

Antigen Type: Synthetic Peptide

Gene Name: NAMPT
Gene ID: 10135
Primary Accession: P43490
NCBI Accession: NP_005737.1
Other Accession: Q80Z29; Q52I78; Q99KQ4
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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