NANOS2 Polyclonal Antibody

Background:
Nanos2, also known as NOS2, is a 138 amino acid protein that contains one nanos-type zinc finger. The nanos-type zinc finger is comprised of two C2HC motifs, each of which are capable of binding one molecule of zinc and each of which work in tandem to play essential roles in translational regulation events. Expressed specifically in male germ cells, Nanos2 is essential for spermatogonia formation and is required to support the self-renewal, proliferation and overall development of proximal germ cells. Additionally, Nanos2 is thought to regulate the translation of target mRNAs, possibly by associating with the 3’-UTR of select transcripts.

Research Area: Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Synonyms:
NANO2, Nanos homolog 2, Nanos homolog 2 Drosophila, NANOS2, NOS-2, NOS2

Immunogen: Recombinant protein of human NANOS2

Swissprot: P60321
Gene Accession: BC117484

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-69188/sc-69190/sc-69187/sc-292082