Nap1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008],function:Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.,subunit:Interacts with IKBKE, TBK1 and TICAM1.,tissue specificity:Widely expressed. Abundant expression seen in the pancreas and testis.,

Synonyms: AZI2, NAP1, 5-azacytidine-induced protein 2, NF-kappa-B-activating kinase-associated protein 1, Nak-associated protein 1, TILP

Gene Name: AZI2

Gene ID: 64343

SwissProt ID: Q9H6S1

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.