NAPRT Polyclonal Antibody

Background:
Nicotinic acid (NA) is a coenzyme in cellular redox reactions, and is an essential component of metabolic pathways in all living cells. NAPRT1 (Nicotinate phosphoribosyltransferase) is essential for increasing cellular NAD levels and, thus, to prevent oxidative stress of cells. NAPRT1 converts Nicotinic acid (NA; niacin) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD).

Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
FHA HIT interacting protein, FHA-HIT-interacting protein, FHIP, NAPRT1, NAPRTase, Nicotinate phosphoribosyltransferase, Nicotinate phosphoribosyltransferase domain containing 1, Nicotinate phosphoribosyltransferase domain-containing protein 1, Nicotinic acid phosphoribosyltransferase, PNCB, PP3856

Immunogen: Fusion protein of human NAPRT

Swissprot: Q6XQN6
Gene Accession: BC032466

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.