NAPRT Polyclonal Antibody

Background:
Nicotinic acid (NA) is a coenzyme in cellular redox reactions, and is an essential component of metabolic pathways in all living cells. NAPRT1 (Nicotinate phosphoribosyltransferase) is essential for increasing cellular NAD levels and, thus, to prevent oxidative stress of cells. NAPRT1 converts Nicotinic acid (NA; niacin) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD).

Research Area: Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
NAPRT, NAPRT1, PP3856

Immunogen: Recombinant fusion protein of human NAPRT1 (NP_660202.3).

Swissprot: Q6XQN6
Gene ID: 93100

Calculated MW: 56 kDa/57 kDa/60 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.