NaV1.7 polyclonal, anti-human, rat

Background:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.

Alternative Name:
hNE-Na, PN1, SCN9A, NENA, ETHA, GEFSP7, hNE Na, hNE-Na, hNENa, NE NA, NENA, Neuroendocrine sodium channel, Peripheral sodium channel 1, PN1, Scn9a, SCN9A, Sodium channel protein type 9 subunit alpha, Sodium channel protein type IX subunit alpha, Sodium channel voltage gated type IX alpha, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha subunit, Voltage gated sodium channel alpha subunit Nav1.7, Voltage gated sodium channel subunit alpha Nav1, Voltage-gated sodium channel subunit alpha Nav1.7,

Application Dilution:
ICC:1:50-1:200
IHC:1:50-1:200

Specificity: NaV1.7 polyclonal antibody detects endogenous levels of NaV1.7 protein.

Immunogen:
Peptide.

MW: 226 kDa

Swiss-Prot: Q15858(Human) O08562(Rat)

Purification & Purity:
Peptide affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.