NBN (clone 7E4A2), anti-human, rat

NBN (clone 7E4A2), anti-human, rat

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In stock
SKU
BT-MCA3273
Catalog Number: BT-MCA3273
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human, rat
Application(s): WB, IHC, ICC, FCM
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Background:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: ATV, NBS, P95, NBS1, AT-V1, AT-V2

Immunogen: Purified recombinant fragment of human NBN (AA: 467-615) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage
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