NBN polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP11776b
Catalog Number: AC-AP11776b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19072
Applications: WB, FC, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19072
Applications: WB, FC, IF
Datasheet
Request Information
Background:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Other Names:
Nibrin, Cell cycle regulatory protein p95, Nijmegen breakage syndrome protein 1, NBN, NBS, NBS1, P95
Target/Specificity:
This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.
Antigen Region:
602-630
Antigen Type: Synthetic Peptide
Gene Name: NBN (HGNC:7652)
Gene ID: 4683
Primary Accession: O60934
NCBI Accession: NP_002476.2
Other Accession: NP_002476.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Other Names:
Nibrin, Cell cycle regulatory protein p95, Nijmegen breakage syndrome protein 1, NBN, NBS, NBS1, P95
Target/Specificity:
This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.
Antigen Region:
602-630
Antigen Type: Synthetic Peptide
Gene Name: NBN (HGNC:7652)
Gene ID: 4683
Primary Accession: O60934
NCBI Accession: NP_002476.2
Other Accession: NP_002476.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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