NBPF1/9/10/12/14/15/16/20 Polyclonal Antibody

Background:
neuroblastoma breakpoint family member 12(NBPF12) Homo sapiens This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This

Alternative Names:
NBPF12, COAS1, KIAA1245, Neuroblastoma breakpoint family member 12, Chromosome 1 amplified sequence 1, NBPF10, Neuroblastoma breakpoint family member 10, NBPF16, Neuroblastoma breakpoint family member

Immunogen: The antiserum was produced against synthesized peptide derived from human NBPF1/9/10/12/14/15/16/20. AA range:121-150

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 36

GeneID: NBPF12

Storage: -20°C/1 year

NOTE: For Research Use Only