NBR1 (7C3) Mouse mAb

Background:
NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.

Cellular localization: Cytoplasm, Cytoplasmic vesicle, Lysosome

Specificity: Human

Alternative Names:
1A13B, MIG19, Nbr1

Immunogen: Recombinant Protein

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: IHC 1:100-200

Observed band: 120kDa

GeneID: 4077

Swiss-Prot No.: Q14596

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only