NCALD polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP10495b
Catalog Number: AC-AP10495b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22143
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22143
Applications: WB
Datasheet
Request Information
Background:
NCALD encodes a member of the neuronal calcium sensor(NCS) family of calcium-binding proteins. The protein contains anN-terminal myristoylation signal and four EF-hand calcium bindingloops. The protein is cytosolic at resting calcium levels; however,elevated intracellular calcium levels induce a conformationalchange that exposes the myristoyl group, resulting in proteinassociation with membranes and partial co-localization with theperinuclear trans-golgi network. The protein is thought to be aregulator of G protein-coupled receptor signal transduction.Several alternatively spliced variants of this gene have beendetermined, all of which encode the same protein; additionalvariants may exist but their biological validity has not beendetermined.
Other Names:
Neurocalcin-delta, NCALD
Target/Specificity:
This NCALD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human NCALD.
Antigen Region:
147-174
Antigen Type: Synthetic Peptide
Gene Name: NCALD
Gene ID: 83988
Primary Accession: P61601
NCBI Accession: NP_001035714.1;NP_001035715.1;NP_001035716.1;NP_001035717.1;NP_001035718.1;NP_001035719.1;NP_001035720.1;NP_114430.2
Other Accession: Q7SY75; Q5PQN0; Q91X97; Q4R4N4; P62758; P61602; P37235; P84076; Q06AT1; P84075; P84074; Q4PL64; NP_001035715.1; NP_001035720.1;
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
NCALD encodes a member of the neuronal calcium sensor(NCS) family of calcium-binding proteins. The protein contains anN-terminal myristoylation signal and four EF-hand calcium bindingloops. The protein is cytosolic at resting calcium levels; however,elevated intracellular calcium levels induce a conformationalchange that exposes the myristoyl group, resulting in proteinassociation with membranes and partial co-localization with theperinuclear trans-golgi network. The protein is thought to be aregulator of G protein-coupled receptor signal transduction.Several alternatively spliced variants of this gene have beendetermined, all of which encode the same protein; additionalvariants may exist but their biological validity has not beendetermined.
Other Names:
Neurocalcin-delta, NCALD
Target/Specificity:
This NCALD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human NCALD.
Antigen Region:
147-174
Antigen Type: Synthetic Peptide
Gene Name: NCALD
Gene ID: 83988
Primary Accession: P61601
NCBI Accession: NP_001035714.1;NP_001035715.1;NP_001035716.1;NP_001035717.1;NP_001035718.1;NP_001035719.1;NP_001035720.1;NP_114430.2
Other Accession: Q7SY75; Q5PQN0; Q91X97; Q4R4N4; P62758; P61602; P37235; P84076; Q06AT1; P84075; P84074; Q4PL64; NP_001035715.1; NP_001035720.1;
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review