NCAM polyclonal, anti-human, mouse, zebrafish

Background:
Neural cell adhesion molecules (NCAMs) are a family of closely related cell surface glycoproteins involved in cell to cell interactions during growth and thought to play an important role in embryogenesis and development. The expression of these molecules is widespread in all three germ layers during embryogenesis, but is more restrictive in adult tissues. NCAM expression is observed in a variety of human tumors including neuroblastomas, rhabdo-myosarcomas, Wilms' tumor, Ewing's sarcoma and some primitive myeloid malignancies. Multiple isoforms of NCAM have been reported in both mouse and human brain tissue. In humans, NCAMs arise from differential splicing and use of alternative polyadenylation sites of a single gene mapping to 11q23.

Alternative Name:
N-CAM-1, NCAM-1, NCAM1, antigen MSK39 identified by monoclonal, 5.1H11, antigen recognized by monoclonal, 5.1H11, CD56, cell adhesion molecule, neural, 1, MSK 39, MSK39, N-CAM-1, NCAM 1, NCAM, NCAM C, NCAM-1, NCAM1, NCAM1, NCAMC, Neural cell adhesion molecule 1, Neural cell adhesion molecule NCAM, OTTHUMP00000235666,

Application Dilution:
WB:1:1,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: NCAM polyclonal antibody detects endogenous levels of NCAM protein.

Immunogen:
recombinant protein

MW: 100-150 kDa

Swiss-Prot: P13591(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.