NCF2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6214
Background:
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
Alternative Name:
67 a neutrophil oxidase factor, Chronic granulomatous disease autosomal 2, NADPH oxidase activator 2, NCF-2, Ncf2, NCF2, Neutrophil cytosol factor 2, Neutrophil NADPH oxidase factor 2, NOXA2, p67-phox, p67phox,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: NCF2 polyclonal antibody detects endogenous levels of NCF2 protein.
Immunogen:
Recombinant full length Human NCF2.
MW: ~ 60 kDa
Swis Prot.: P19878
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). Defects in NCF2 are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2). Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.
Alternative Name:
67 a neutrophil oxidase factor, Chronic granulomatous disease autosomal 2, NADPH oxidase activator 2, NCF-2, Ncf2, NCF2, Neutrophil cytosol factor 2, Neutrophil NADPH oxidase factor 2, NOXA2, p67-phox, p67phox,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: NCF2 polyclonal antibody detects endogenous levels of NCF2 protein.
Immunogen:
Recombinant full length Human NCF2.
MW: ~ 60 kDa
Swis Prot.: P19878
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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