NCF2 Polyclonal Antibody

Background:
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Metabolism, Immunology

Synonyms:
67 kDa neutrophil oxidase factor, Chronic granulomatous disease autosomal 2, FLJ93058, NADPH oxidase activator 2, NCF-2, Ncf2, NCF2, Neutrophil cytosol factor 2, Neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2), Neutrophil NADPH oxidase factor 2, NOXA2, P67 PHOX, p67-phox, p67phox

Immunogen: Recombinant protein of human NCF2

Swissprot: P19878
Gene Accession: BC001606

Calculated MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7662/sc-7663/sc-15342