NCK2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: GRB4, NCKbeta

Cellular Location: Endoplasmic reticulum

Immunogen:
Recombinant protein of human NCK2

Gene Symbol: NCK2

Gene ID: 8440

Swiss prot: O43639

Calculated MW: 43kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.