NCK2 Polyclonal Antibody

Background:
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Tags and Cell Markers

Synonyms:
NCK2, GRB4, NCKbeta

Immunogen: Recombinant fusion protein of human NCK2 (NP_003572.2).

Swissprot: O43639
Gene ID: 8440

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.