GPR52 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP70208
Catalog Number: AC-AP51865
Size: 100 µl
Host: Rabbit
Applications: WB, ICC, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, ICC, E
Datasheet
Request Information
Background:
Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).
Other Names:
GPR52; Probable G-protein coupled receptor 52
Antigen Type: synthetic peptide
Antigen Type: GPR52 {ECO:0000303|PubMed:9931487, ECO:0000312|HGNC:HGNC:4508}
Gene ID: 9293
Primary Accession: Q9Y2T5
Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).
Other Names:
GPR52; Probable G-protein coupled receptor 52
Antigen Type: synthetic peptide
Antigen Type: GPR52 {ECO:0000303|PubMed:9931487, ECO:0000312|HGNC:HGNC:4508}
Gene ID: 9293
Primary Accession: Q9Y2T5
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