NCOA1 Polyclonal Antibody

Background:
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74

Immunogen: Recombinant fusion protein of human NCOA1 (NP_003734.3).

Swissprot: Q15788
Gene ID: 8648

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.