NCOA4 Polyclonal Antibody

Background:
This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Research Area: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
70 kDa androgen receptor activator, 70 kDa androgen receptor coactivator, 70 kDa AR activator, 70 kDa AR-activator, Androgen receptor coactivator 70 kD, Androgen receptor coactivator 70 kDa protein, Androgen receptor-associated protein of 70 kDa, ARA 70, ARA70, DKFZp762E1112, ELE 1, ELE1, ELE1/ret TK, NCOA 4, NCoA-4, NCOA4, NCOA4, Nuclear receptor coactivator 4, Papillary thyroid carcinoma 3, PTC 3, PTC3, RET activating gene ELE1, Ret activating protein ELE1, Ret-activating protein ELE1, RFG

Immunogen: Fusion protein of human NCOA4

Swissprot: Q13772
Gene Accession: BC012736

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 2.04 mg/mL
Dilution: IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.