NCOR1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1121a
Background:
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Other Names:
Nuclear receptor corepressor 1, N-CoR, N-CoR1, NCOR1, KIAA1047
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1121a was selected from the N-term region of human NCOR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NCOR1
Gene ID: 9611
Primary Accession: O75376
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Other Names:
Nuclear receptor corepressor 1, N-CoR, N-CoR1, NCOR1, KIAA1047
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1121a was selected from the N-term region of human NCOR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NCOR1
Gene ID: 9611
Primary Accession: O75376
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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