NCOR1 polyclonal, anti-human

Background:
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Synonyms: N-CoR, TRAC1, N-CoR1, hN-CoR

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human NCOR1

Gene Symbol: NCOR1

Gene ID: 9611

Swiss prot: O75376

Calculated MW: 270/259/104kDa

Recommended dilution:
IHC 1:100-300

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.